Research: Congenital Insensitivity to Pain (with Anhhdrosis)
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Congenital Insensitivty to Pain with Anhidrosis is a rare disorder of the nervous system that prevents the feeling of pain or temperature1. It also prevents sweating, which makes the person more susceptible to heatstroke.
The absence of pain makes them more likely to suffer self-injury, especially in childhood. Injuries may take longer to heal due to re-injury and may become infected. Joint and bone problems from repeated injuries are common.
There is no treatment for CIPA.
Approximately 20% of people with CIPA die of hyperthermia (fevers) by age 31. Hyperthermia may cause seizures.